More Efficient Together
Junior BE WISE+
Biologically active food supplement
The source of iodine for physical, psychological and mental growth
The harmonious development
|Biologically active food supplement Junior BE WISE+ promotes the elimination of iodine deficiency in the body of the child. It improves thefunction of brain activity. Strengthens the immune system, regulates all body systems, normalizes metabolism.|
The natural complex Junior BE WISE+ regulates metabolism as well as functions of the nervous system and brain. Enhances responsiveness, attention focusing, memory and assiduity. Balanced formula of the complex enhances performance of the digestive tract and promotes improvement of appetite.
Biologically active food supplement Junior BE WISE+ beneficially impacts mood and ensures better sleep. Junior Be Wise+ is a secret of balanced mental, physical and intellectual development of your child.
Selenium and iodine — key ingredients of the complex—are indispensable microelements for kids’ health, responsible for thinking skills and energy of a child.
Iodine — one of the most important trace elements for the development of the child. Participates in the construction of the thyroid hormones that regulate energy metabolism, actively influence the physical and mental development and maturation of tissues, involved in the regulation of central nervous system, affects the activity of all systems of the body of the child. Iodine contributes to normalization of the thyroid gland performance and improves the synthesis of its hormones that promote development of the nervous system and activity of neurons.
|World Health Organization (WHO) notes that 60% of children in Eastern Europe there is a lack of iodine in the body. It is fraught with a number of negative consequences: children significantly disturbed mental function, delayed growth, reduced resistance to infections.|
Vitamins B1, B6, PP — regulate the activity of all body systems, normalize metabolism, are particularly important for vision. Vitamin D3 promotes the fullest absorption of calcium by bone tissue, regulates calcium and phosphorus metabolism.
Vitamins C and E — are antioxidants, energy-fed cells, strengthen the immune and nervous systems. Beta-carotene (in the human body turns into vitamin A activity) protects cell membranesfrom the damaging effects of free radicals. Micronutrients (magnesium, iron, zinc) — support and the energy status of the child’shealthy growth.
- Makes up for deficiency of vitamins and iodine in the child’s body.
- Ensures balanced comprehensive development of a child.
- Beneficially influences mental, physical and intellectual growth of children.
- It improves the function of brain activity.
- Improves responsiveness, attention focusing, memory and assiduity.
- Strengthens and supports the nervous system performance.
- Strengthens the immune system.
- Regulates the activity of all body systems.
- It normalizes the metabolism.
- Regulates calcium and phosphorus metabolism.
- Helps strengthen the overall body of the child.
- Support and the energy status of the child’s healthy growth.
- Alleviates irritability, improves sleep.
- Regulates metabolism and energy status of the child’s body.
- Has a positive impact on the digestive tract, improves appetite.
- Protects against the damaging effects of free radicals.
Target audience to take Junior Be Wise+:
- All kids for balanced comprehensive development;
- Children who suffer from deficiency of iodine, vitamins and minerals;
- Children subject to intellectual and physical overstrains;
- Children who need to support metabolism and energy status of the body.
- The complex beneficially influences the mood, as it sustains nervous system and alleviates irritability.
- Junior Be Wise+ contains iodine, which is vital for proper mental, physical and intellectual development of a child.
- Vitamins and minerals in Junior Be Wise+ complex are balanced so that the body assimilates them completely and ensure balanced growth.
- This product is very usable—chewable tablets with a strawberry flavor remind kids tasty sweets.
Ingredients Per 1 tablet:
- Beta carotene — 0.75 mg
- Vitamin E — 1.7 mg
- Vitamin D3 — 0.75 µg
- Vitamin C — 14.5 mg
- Vitamin B1 — 0.25 mg
- Vitamin B2 — 0.3 mg
- Vitamin B6 — 0.3 mg
- Vitamin B9 — 50 µg
- Vitamin B12 — 0.25 µg
- Vitamin PP — 3 mg
- Magnesium — 22.5 mg
- Iron — 1.5 mg
- Zinc — 1.15 mg
- Chromium — 10 µg
- Manganese — 0.3 mg
- Copper — 0.08 mg
- Selenium — 5 µg
- Iodine — 10 µg
Recommended as a biologically active food supplement, an additional source of the group B vitamins (B1, B2, B6, B12), as well as vitamins PP, C, E, D3, folic acid, beta-carotene and microelements (iron, manganese, selenium, chromium, magnesium, iodine).
Packaging: 60 chewable tablets of 756 mg.
Contraindications: Individual intolerance of the product components.
Precautions: The recommended daily intake should not be exceeded.
DIRECTIONS OF USE: Recommended for children from 4 to 10 years old to take 1 tablet per day during meals. For children over 11 years old to take 2 tablets per day during meals.
Storage conditions: Keep at room temperature (not exceeding 250C) in a dry place out of reach of children.
Shelf life: 3 years.
Manufacturer: «Nutripharma Ltd», Unit 507-Western Estate-Ballynaneashagh-Waterford, Ireland Group of Companies «Arkopharma Laboratoires Pharmaceutiqes», France.
PROPERTIES OF THE COMPONENTS
According to the US National Institute of Health, magnesium is need for more than 300 biochemical processes in the body. It helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and keeps bones strong. Magnesium also helps regulate blood sugar levels, promotes normal blood pressure, and is known to be involved in energy metabolism and protein synthesis. There is increased recognition of the role of magnesium in preventing and managing disorders such as hypertension, cardiovascular disease, and diabetes.
Magnesium has a cardioprotective effect, providing a beneficial effect on heart rhythm disturbances, coronary heart disease, myocardial infarction, improving myocardial oxygen supply. At the same time, magnesium exhibits vasodilator effect and helps reduce blood pressure. Magnesium is an anti-stress macro-elements, has a normalizing effect on the nervous system and its higher parts (especially in combination with vitamin B6) with nervous tension, depression, neurosis.
Magnesium in diabetes prevents cardiovascular complications and, in combination with zinc, chromium, selenium improves the function of beta cells of the pancreas. In diseases of the respiratory system enhances the removal of the bronchi and bronchospasm. In both cases, magnesium is an important factor in therapy (in combination with fixed assets).
Magnesium has a positive impact on the reproductive system. In pregnant women, magnesium deficiency prevents the development of the fruit (along with folic and pantothenic acid), the development of gestosis, premature births and miscarriages. At the time of menopause in women reduces the negative manifestations of this condition.
Zinc supports normal growth and development during pregnancy, childhood, and adolescence. It stimulates the activity of approximately 100 enzymes that promote biochemical reactions in the body. Zinc supports a healthy immune system, is needed for wound healing, helps maintain the sense of taste and smell and is needed for DNA synthesis. Zinc plays an important role in the hormonal functions in the body. It affects the production and functioning of insulin,and thus the entire spectrum of insulin-dependent processes.
In men, zinc is involved in the synthesis of testosterone and functioning of sex glands, there is a relationship between the level of zinc in the body and potency.Zinc regulates the level of metabolites of testosterone — dihydrotestosterone, which causes an excess of prostate hyperplasia. Zinc is an essential factor for the female body, as part of the structure of the receptors for estrogen, thus regulating all estrogen-dependent processes.
Zinc is vital for the functioning of the thymus and the normal state of the immune system. Zinc with vitamin A (vitamin C) prevents the formation of immune deficiencies, stimulating the synthesis of antibodies, and providing antiviral effect. Zinc has a wound-healing and yazvozazhivlyayuschim action, the processes involved in perception of taste and smell, is essential for the functioning of the central nervous system, including the processes of remembering.
Iron is a trace mineral found in the hemoglobin molecule of red blood cells, the part of the blood that carries oxygen from the lungs to the rest of the body. It is also found in myoglobin, the form of hemoglobin found in muscle tissue. Iron works with several enzymes required for energy production and protein metabolism.
The most obvious form of manifestation of iron deficiency — iron deficiency anemia, in which serious violations may be lurking in the body (chronic blood loss with internal bleeding). As a rule, reduction in hemoglobin in the blood of the diagnosis — anemia. By the end of pregnancy iron-deficiency anemia occurs in 30-73% of women. Iron deficiency anemia is often the first year of life of children. Iron deficiency in children can slow the mental and physical development, causing a distortion of appetite.
Most doctors recommend that pregnant women take a supplement containing iron since the increased demand for iron can rarely be met through diet alone during pregnancy. Many women’s vitamin formulas include iron, which can be useful for menstruating women. After menopause, most women do not need extra iron.
Iron is an essential component of proteins involved in oxygen transport. It is also essential for the regulation of cell growth and differentiation. A deficiency of iron limits oxygen delivery to cells, resulting in fatigue, poor work performance, and decreased immunity.
Manganese — a micro-element, which is necessary for the functioning of enzymes involved in the formation of bone and connective tissue, the regulation ofgluconeogenesis. Actively influences the cholesterol biosynthesis, metabolism of insulin and other types of metabolism. In most cases the manganese is not astructural enzymes of the Component, but it affects their catalytic activity.
Manganese is of particular importance in maintaining the functions of sexual glands, musculoskeletal, nervous and immune systems. This micro-elementneeded for the prevention of diabetes, thyroid disease, coronary artery disease of the heart.
Copper plays an important role in the biosynthesis of hemoglobin. Therefore, its disadvantage, as well as iron, can lead to anemia. Copper plays an important role in antioxidant protection, together with zinc is part of the tissue antioxidant enzymes — superoxide dismutase and antioxidant proteins of blood plasma — tserruloplazmina, who is a carrier of this metal.
Copper has anti-inflammatory and antiseptic properties (possibly due to antioxidant action.) Regulates the metabolism of catecholamines, serotonin, tyrosine, melanin, enhances the activity of insulin and a more complete utilization of carbohydrates. This trace mineral is involved in the formation of the protein structure of the connective tissue — collagen and elastin, which are structural components of bone and cartilage, skin, lungs, blood vessel walls.
Therefore, copper deficiency can lead to the formation of an aneurysm of the aorta and cerebral vessels. For this reason, copper deficiency leads to bone demineralization and osteoporosis. Copper is involved in the formation of myelin sheaths of nerve degeneration, which leads to multiple sclerosis and other serious disorders of the nervous system. Copper participates in reductive-oxidative processes and the synthesis of hemoglobin, stimulates the formation of red blood cells and contributes to an increase in insulin activity and the more complete utilization of carbohydrates.
Main biological role of micro-element chromium is in the regulation of carbohydrate metabolism and blood glucose levels because chromium is a component of low molecular weight organic compound — «glucose tolerance factor.»
Chromium increases the sensitivity of cellular insulin receptors, facilitating their interaction and decreasing the body’s need for insulin. He is able to enhance insulin action in all metabolic processes regulated by this hormone. Therefore, chromium is required with diabetes (primarily type II).
Deficiency of this micro-element can cause diabetopodobnogo state. The level of chromium lowers a woman during pregnancy and after birth.
Chromium is essential for the prevention of diabetes and cardiovascular disease.In addition, in experiments on animals showed that chromium deficiency results in stunted growth, causes neuropathy and a disorder of higher nervous activity, reduces the fertilizing capacity of sperm. It should be emphasized that the abuse of sugar increases the need for chromium and at the same time, its loss in the urine.
Selenium is a synergist of vitamin E and promotes its antioxidant activity. Selenium deficiency leads to weakening of the antioxidant status, anticarcinogenic protection, causes myocardial, impaired sexual function, immune deficiency.
As well as selenium exhibits antimutagenic, antiteratogenny, radioprotector effect, stimulates the antitoxic protection, normalizes exchange of nucleic acids and proteins, improves fertility, normalizes exchange of eicosanoid, regulates the function of the thyroid gland and pancreas. In view of the above applies to selenium geroprotectors.
Selenium has many functions, is extremely important for normal functioning of the internal organs, protein synthesis, defense against toxic substances entering the human body. This trace mineral is extremely necessary to maintain male reproductive function of the body, has a significant effect on the eyes, skin conditions, is involved in metabolism.
Selenium increases our resistance to adverse environmental conditions, viruses, thus protecting us from various diseases. Selenium is required for heart muscle and blood vessels.
Iodine is a trace element necessary for the normal function of the thyroid gland. Specifically, the thyroid gland uses iodine in the production of the thyroid hormone. Iodine deficiency can result in goiter (a condition in which the thyroid becomes enlarged in an effort to compensate for the body’s lack of iodine), as well as impaired mental and physical development in children. Iodine deficiency during pregnancy can cause miscarriage and increased risk of infant mortality.
Iodine deficiency leads to a decrease in basal metabolism. First of all, it affects the state of the central nervous system. The child should receive the necessaryamount of iodine in the womb. In children, hypothyroidism leads to profound disturbances of higher nervous activity, incomplete development of intellectual capacities. In adults, iodine deficiency leads to mental inertia, lethargy, decreased mental ability, strength anda decrease in heart rate, «slagging». At the same time inhibited the oxidation ofcholesterol and its accumulation of atherogenic form that leads to earlyatherosclerosis, and in combination with disorders of the cardiovascular system -to myocardial infarction and stroke. Iodine deficiency results in immune deficiency, increased risk of cancer, especially of the thyroid gland. Nosological manifestation of iodine deficiency isendemic goiter.
Beta-carotene is a biological antioxidant. It protects cell membranes against the effects of free radicals. Beta-carotene is a predecessor of vitamin A («the growth vitamin»); it regulates the growth of bones and participates in the formation of optic pigments that are necessary for normal night and color vision.
Vitamin A and its analogs have shown the ability to help inhibit cancer cell proliferation and help in returning to normal growth patterns. Individuals with highest levels of beta-carotene intake have lower risks of lung cancer, coronary artery heart disease, stroke and age-related eye disease than individuals with lowest lvels of beta-carotene intake. Its inhibitory effects are especially potent against leukemia and certain head and neck cancers.
Beta-carotene may have a role to play in staving off heart disease, apparently a function of its ability to keep harmful LDL cholesterol from damaging the heart and coronary arteries. Beta-carotene has been shown to have benefits to the immune system.
Like all other carotenoids, beta-carotene is an antioxidant. Antioxidants are substances that help prevent or reduce the formation of damaging chemicals in the body called free radicals. Consuming foods rich in beta-carotene appears to protect the body from damaging molecules called free radicals. Free radicals cause damage to cells through a process known as oxidation, and over time, such damage can lead to a variety of chronic illnesses. Beta-carotene’s antioxidant actions make it valuable in protecting against, and in some cases even reversing, precancerous conditions affecting the breast, mucous membranes, throat, mouth, stomach, prostate, colon, cervix, and bladder.
Thiamine works with the other B vitamins to change protein, carbohydrate, and fat to energy. It is especially vital for changing carbohydrates to energy. It is a key factor in the healthy functioning of all the body’s cells, especially the nerves.
Vitamin B1 helps the body cells convert carbohydrates into energy. It is also essential for the functioning of the heart, muscles, and nervous system. As a coenzyme, thiamin plays a key role in energy production, conversion of glucose to fat. Every cell of the body requires vitamin B1 to form the fuel the body runs on — ATP. Nerve cells require vitamin B1 in order to function normally.
Thiamin is needed for the metabolism of carbohydrates, fat, and protein. It is especially involved in carbohydrate metabolism in the brain.
Thiamin may be used to support nerve health, and minimize numbness and tingling, helping to protect against this condition. Thiamine aids the nervous system and is essential for the functioning of important enzymes. These enzymes have vital roles in the processes that make energy available in the body. Thiamine is essential for the transmission of certain types of nerve signal between the brain and the spinal cord. Depression, poor memory, muscle weakness and stiffness, nerve tingling, burning sensation and numbness, tiredness, headache, loss of appetite and nausea are some of the symptoms and signs of its deficiency.
Riboflavin is an integral component of the coenzymes that participate in many energy-yielding metabolic pathways. Like its close relative vitamin B1 (thiamine), riboflavin plays a crucial role in certain metabolic reactions, particularly the conversion of carbohydrates into sugar, which is «burned» to produce energy. They promote the first steps in the metabolism (breakdown and production) of glucose and of fatty acids. The metabolism of some vitamins and minerals also require riboflavin. Riboflavin is essential for tissue respiration and the generation of energy from the carbohydrates, acids and fats. It is important for body growth and red blood cell production and helps in releasing energy from carbohydrates.
Vitamin B2 helps prevent and is used to treat migraine headaches, cataracts, rheumatoid arthritis, and a number of skin disorders such as acne (acne rosacea), dermatitis, and eczema. In the treatment of anemia, adding Vitamin B2 to iron supplements has shown to increase its effectiveness. Vital to maintaining a proper metabolism, riboflavin also helps to shore up the immune system by reinforcing antibody reserves, the body’s first line of defense against infection. Along with iron, riboflavin is essential for producing the red blood cells that carry oxygen throughout the body. In addition, the body uses extra riboflavin to keep tissue in good repair and speed healing of wounds, burns and other injuries.
Along with such B vitamins as vitamin B6 and niacin (which it helps the body convert into active forms), riboflavin protects the nervous system. It may therefore have a role to play in treating nervous system conditions such as numbness and tingling, Alzheimer’s disease, epilepsy, multiple sclerosis, and even anxiety, stress, and fatigue. Carpal tunnel syndrome may benefit from a treatment program including this vitamin when combined with vitamin B6. The body needs vitamin B2 for reproduction and it also enhances the immune system’s ability to fight disease.
Riboflavin is vital for normal reproduction, growth, repair and development of body tissues including the skin, hair, nails, connective tissue and immune system. Riboflavin (vitamin B2) works with the other B vitamins. Dietary and supplemental vitamin B2, along with other nutrients is important for normal vision and prevention of cataracts. Riboflavin’s ability to improve the skin’s secretion of mucus may aid in clearing up skin pustules associated with rosacea.
Vitamin B6 supports more vital bodily functions than any other vitamin. Vitamin B6 is a coenzyme for several enzyme systems. Vitamin B6, used mainly in the body for the processing of amino acids, performs this task along with certain enzymes. It is vital in the metabolism of amino acids in the intestines. It allows the amino acids to be synthesized, broken down and absorbed. The forming of histamine, serotonin, dopamine and adrenaline are dependent on vitamin B6. Vitamin B6 is required for the production of serotonin and helps to maintain healthy immune system functions, to protect the heart from cholesterol deposits, and to prevent kidney stone formation.
Vitamin B6 is indicated for the treatment of sideroblast anemia, neurologic disturbances, seborrhoeic dermatitis, and cheilosis. In combination with folic acid and vitamin B12, vitamin B6 lowers homocysteine levels which is an amino acid linked to heart disease and stroke, and possibly other diseases as well, such as osteoporosis, and Alzheimer’s disease.
Pyridoxine is required for the balancing of hormonal changes in women as well as assisting the immune system and the growth of new cells. Vitamin B6 may be helpful in some women with premenstrual dysphoric disorder, also known as premenstrual syndrome (PMS), and may be useful in some cases of gestational diabetes and for protection against metabolic imbalances associated with the use of some oral contraceptives. Vitamin B6 promotes iron excretion and this has been used as a rationale for treatment in iron storage diseases.
Folic acid plays an essential role in human growth and development, in particular cell division and DNA synthesis. Folic acid is involved in every bodily function that requires cell division. Folic acid works along with vitamin B12 and vitamin C to help the body digest and utilize proteins and to synthesize new proteins when they are needed. Folic acid is important for any stage of human life which involves growth such as pregnancy, lactation and early growth because of the role the folate plays in DNA, RNA and protein production.
Folic acid is indicated for the prevention of some birth defects and appears to confer significant protection against cardiovascular disease and some forms of cancer. Folic acid may be used in the treatment of disorders associated with folic acid deficiency and may also be part of the recommended treatment for certain menstrual problems and leg ulcers. Folic acid also helps with tissue growth and cell function. In addition, it helps to increase appetite when needed and stimulates the formation of digestive acids.
Pregnant women have an increased need for folic acid, both for themselves and their child. Folic acid also is crucial to support the rapid growth of the placenta and fetus. Taken as part of a B-complex vitamin that contains biotin and vitamin B12, folic acid can strengthen the reproductive system in women having trouble conceiving. Without adequate amounts of folic acid, cell division could be impaired, possibly leading to poor growth in the fetus or placenta. Adequate intake of folic acid is vital for the prevention of several types of birth defects, particularly neural tube defects.
Folic acid appears to regulate the body’s production and use of homocysteine. High levels of a substance called homocysteine in the blood is considered to be a risk factor for heart disease. People who are at high risk of strokes and heart disease may greatly benefit by taking folic acid supplements. High levels of homocysteine have also been found to contribute to problems with osteoporosis. Folic acid, together with vitamins B6 and B12, helps break down homocysteine, and may help reverse the problems associated with elevated levels.
Folate status is associated with colorectal, lung, esophageal, brain, cervical and breast cancers. Folate is involved in the synthesis, repair, and functioning of DNA, our genetic map, and a deficiency of folate may result in damage to DNA that may lead to cancer. Folate is important for cells and tissues that rapidly divide.
Because folic acid is often deficient in those who are depressed, a supplement may help. Vitamin B9 (folate) may be associated with depression more than any other nutrient, and may play a role in the high incidence of depression in the elderly.
Folate deficiency appears to be linked to cervical dysplasia. Experts recommend getting adequate amounts of folate in the diet for all wome, which may be particularly important for those with risk factors for cervical dysplasia such as an abnormal pap smear or genital warts.
Vitamin B12’s main functions are in the formation of red blood cells and the maintenence of a healthy nervous system. Vitamin B12 is an especially important vitamin for maintaining healthy nerve cells and it aids in the production of DNA and RNA, the body’s genetic material. Cyanocobalamin works to promote normal growth and development, helps with certain types of nerve damage, and treats pernicious anemia. Vitamin B12 helps in the formation of red blood cells and in the maintenance of the central nervous system. Nerves are surrounded by an insulating fatty sheath comprised of a complex protein called myelin. B12 plays a vital role in the metabolism of fatty acids essential for the maintainence of myelin. Prolonged B12 deficiency can lead to nerve degeneration and irreversible neurological damage.
Vitamin B12 is essential for the proper production of blood platelets and red and white blood cells, the manufacture of vital substances needed for cell function, and the metabolism of nutrients necessary for cell growth. It participates in a variety of cellular reactions to release energy from carbohydrates, fats and protein. Vitamin B12 helps maintain the myelin sheath that insulates nerve fibres from each other. People with vitamin B12 deficiency show irregular destruction of the myelin sheaths, which eventually causes paralysis and death. Vitamin B12 levels decrease with age and various measures of cognitive impairment are associated with reduced B12 status. The most important use of vitamin B12 is to treat the symptoms of pernicious anemia.
Vitamin B9 (folate) and vitamin B12 are critical to the health of the nervous system and to a process that clears homocysteine from the blood. Vitamins B12, B6, and B9 (folate) work closely together to control blood levels of the amino acid homocysteine. Elevated plasma homocysteine concentrations are considered to be a risk factor for vascular disease and birth defects such as neural tube defects.
Vitamin C (ascorbic acid) increases the body’s resistance to infectious diseases, regulates reductive-oxidative processes, carbohydrate exchange, blood coagulation and the regeneration of tissues. It possesses antioxidant qualities and helps reduce the risk of cancer.
Vitamin C is an antioxidant that protects the eyes, heart, and circulatory systems against free radicals. Vitamin C is also believed to protect genetic information against harmful mutations.Ascorbic acid is required for collagen synthesis and has a structural role in bone, cartilage and teeth.
The antioxidant properties of vitamin C — Vitamin C is one of many antioxidants. Antioxidants are nutrients that block some of the damage caused by free radicals, which are by-products that result when our bodies transform food into energy. Vitamin C neutralizes potentially harmful reactions in the watery parts of the body, such as the blood and the fluid inside and surrounding cells.
Vitamin C may help decrease total and LDL cholesterol and triglycerides, as well as increase HDL levels. Vitamin C’s antioxidant activity may be helpful in the prevention of some cancers and cardiovascular disease. The antioxidant properties of vitamin C are thought to protect smokers, as well as people exposed to secondhand smoke, from the harmful effects of free radicals. Vitamin C strengthens the collagen structure of arteries, lowers total cholesterol, and blood pressure, an inhibits platelet aggregation.
Vitamin C may protect against heart disease by reducing the stiffness of arteries and the tendency of platelets to clump together. Vitamin C may have cancer-preventive activity, at least for certain types of cancer. As a powerful antioxidant, vitamin C may help to fight cancer by protecting healthy cells from free-radical damage and inhibiting the proliferation of cancerous cells.
Vitamin C may be useful as an immune stimulator and modulator in some circumstances. Vitamin C promotes resistance to infection through the immunologic activity of leukocytes, the production of interferon, and the process of inflammatory reaction, or the integrity of the mucous membranes. Vitamin C stimulates the immune system.
The role of vitamin D is usually associated only with providing the body with calcium and phosphorus and the formation of the skeleton. However, its physiological function is much wider. Vitamin D plays an important role in the mineralization of bone, cartilage maturation and maturation of collagen, activates reparative processes in the epithelium. It normalizes the functions of the blood-formation and immune systems.
Established the important role of vitamin D in the functioning of muscle and stimulation of protein synthesis, and its production of ATP. Recently identified as immunomodulatory function of vitamin D.
Linked to this is the effectiveness of vitamin D in psoriasis, rheumatoid arthritis.Vitamin D helps in the prevention of cancer pathology. Vitamin D is used to prevent and treat rickets, osteoporosis, hair loss, weeping eczema, for healing wounds and ulcers. Deficiency of vitamin C, B2, K and E reduces the therapeutic efficacy of vitamin D. In humans, vitamin D can be synthesized in the skin when exposed to sunlight from its predecessor D-7-digidroholesterina.
The most important function of vitamin E is to maintain the integrity of the body’s intracellular membrane by protecting its physical stability and providing a defense line against tissue damage caused by oxidation. Vitamin E is protective because it helps reduce oxidation of lipid membranes and the unsaturated fatty acids and prevents the breakdown of other nutrients by oxygen.
Vitamin E is an antioxidant that prevents free radical damage in biological membranes. Free radicals can cause cell damage that may contribute to the development of cardiovascular disease and cancer. Vitamin E has an effect on several enzyme activities and membrane properties. It is involved in the regulation of vascular smooth muscle cell proliferation and protein kinase C activity. Vitamin E as an antioxidant helps to stabilize cell membranes and protect the tissues of the skin, eyes, liver, breast, and testes, which are more sensitive to oxidation.
Vitamin E helps protect against heart disease by limiting the oxidation of LDL-cholesterol. Vitamin E helps prevent oxidation of lipoproteins, particularly in smokers, and reduces the stickiness of platelets in the bloodstream. Vitamin E also keeps arteries flexible and elastic, allowing blood to flow freely. Vitamin E helps prevent arteries from clogging by blocking the conversion of cholesterol into the waxy fat deposits called plaque that stick to blood vessel walls. Vitamin E also thins the blood, allowing for blood to flow more easily through arteries even when plaque is present. Vitamin E also may help prevent the formation of blood clots, which could lead to a heart attack. Vitamin C and vitamin E, taken in combination, help to stabilise LDL cholesterol in the body. This may help to reduce the risk of atherosclerosis.
Some cancers are believed to result from oxidative damage to DNA caused by free radicals. Free radicals can damage DNA, leading to mutations in cells that may cause cancer. Antioxidants such as vitamin E help protect against the damaging effects of free radicals. The vitamin may also help fight cancer by boosting the immune system. Vitamin E may protect against the development of cancers by enhancing immune function. Some evidence associates higher intake of vitamin E with a decreased incidence of prostate cancer and breast cancer. Cigarette smokers have a higher risk of developing cancers of the mouth, upper airways and lungs, and vitamin E may help protect smokers against these cancers through its antioxidant properties.
Because of it’s antioxidant action, vitamin E may help to protect against cataracts and age related macular degeneration. Cataracts are growths on the lens of the eye that cloud vision. They increase the risk of disability and blindness in aging adults. Lens clarity, which is used to diagnose cataracts, is better in regular users of vitamin E supplements and in persons with higher blood levels of vitamin E. Uveitis is another eye disorder for which the antioxidant vitamins C and E may be helpful. Uveitis is inflammation of the uvea, the middle layer of the eye between the sclera and the retina.
Alzheimer’s disease is a wasting disease of the brain. Oxidative stress is believed to contribute to the development of Alzheimer’s disease. Vitamin E is an antioxidant that prevents free radical damage in biological membranes. Vitamin E supplementation improves cognitive performance in healthy individuals and in those with dementia from causes other than Alzheimer’s disease. In addition, vitamin E, together with vitamin C may prevent the development of Alzheimer’s disease.
Vitamin PP (vitamin B3)
Niacin and niacinamide are the two main forms of vitamin B3. Both substances are key in releasing energy from carbohydrates, processing alcohol, forming fats, and producing sex hormones. A significant benefit of niacin is its ability to prevent recurrent heart attack. Niacin also helps regulate cholesterol levels. A third form of niacin, inositol hexaniacinate, is gaining acceptance as a substitute for niacin. Inositol hexaniacinate is composed of one molecule of inositol (an «unofficial» B vitamin) and six molecules of niacin.
Vitamin PP is used in diseases of the heart and liver, stomach ulcers and 12 duodenal ulcer, enterocolitis, weak healing ulcers and wounds, infectiousdiseases.
There is evidence of the effectiveness of vitamin РР in combination with vitamin E in the treatment of mild forms of diabetes. Vitamin PP also provides an effective action for the treatment of alcoholism and drug psychoses. Its deficiency leads to development of dermatitis and symptoms indicating a violation of the nervous system and gastrointestinal tract: nausea, loss of appetite, discomfort in the stomach, severe weakness, memory impairment.